Avtor/Urednik		Pšeničnik, M; Jezernik, K
Naslov		The role of the Golgi apparatus during terminal differentiation of mouse urothelial surface cells
Tip		članek
Vir		Eur J Histochem
Vol. in št.		Letnik 44
Leto izdaje		2000
Obseg		str. 345-51
Jezik		eng
Abstrakt		The development of the Golgi apparatus in the surface cells of mouse urinary bladder during embryonic development was investigated by electronmicroscopic cytochemistry. The distributions of NADPase and TPPase activities were studied in the urinary bladder during day 15 to day 18 of gestation. At the early embryonic stage, the products of the NADPase and TPPase reactions were visible exclusively in 1 to 2 medial and/or trans Golgi saccules. The strongest increment of NADPase and TPPase positive Golgi cisternae was detected at day 17 when the activity of the urothelial cells was very prominent. At this age, NADPase activity was detected also in lysosomes and on the apical surface of the urothelial cells. The highest distribution pattern of NADPase and TPPase activities observed at this stage rapidly decreases at day 18 of fetal life. The results suggest that the organization of the Golgi apparatus reflected the intensity of the processes occuring in the urothelial cells during gestation.
Deskriptorji		BLADDER UROTHELIUM GOLGI APPARATUS CELL DIFFERENTIATION MICE GESTATIONAL AGE THIAMINE PYROPHOSPHATASE NADPH DEHYDROGENASE HISTOCYTOCHEMISTRY MICROSCOPY, ELECTRON