Avtor/Urednik		Meglič, Bernard; Graus, Francesc; Grad, Anton
Naslov		Anti-Yo-associated paraneoplastic cerebellar degeneration in a man with gastric adenocarcinoma
Tip		članek
Vir		J Neurol Sci
Vol. in št.		Letnik 185
Leto izdaje		2001
Obseg		str. 135-8
Jezik		eng
Abstrakt		Paraneoplastic cerebellar degeneration (PCD) with anti-Yo antibodies is almost always associated with ovarian and breast cancer. We describe a man with anti-Yo-positive PCD and gastric adenocarcinoma. The tumor cells were labeled with anti-Yo antibodies by immunohistochemistry. High serum titers of anti-Yo antibodies were found before surgery and decreased 6 months after resection of the tumor. The expression of Yo antigens by the tumor and the decrease in anti-Yo antibody titers after its removal suggest that the immune response against the Purkinje cells of the cerebellum was triggered by the tumor.
Deskriptorji		PARANEOPLASTIC SYNDROMES CEREBELLAR NEOPLASMS STOMACH NEOPLASMS ADENOCARCINOMA AGED IMMUNOHISTOCHEMISTRY