Avtor/Urednik		Tepeš, Bojan
Naslov		Antibiotiki in razjeda želodca in dvanajstnika
Prevedeni naslov		Antibiotics and gastric and duodenal ulcer
Tip		članek
Vir		In: Mueller-Premru M, Gubina M, editors. Mikrobi in antibiotiki 2001. Zbornik predavanj Mikrobiološki simpozij z mednarodno udeležbo; 2001 jun 22-23; Ljubljana. Ljubljana: Slovensko zdravniško društvo, Sekcija za klinično mikrobiologijo in hospitalne infekcije,
Leto izdaje		2001
Obseg		str. 97-105
Jezik		slo
Abstrakt		Infection with Helicobacter pylori is the etiological cause of more than 70% of gastric ulcers and 95% of duodenal ulcers. In Slovenia, antimicrobial therapy is the treatment of choice for benign ulcer disease. Two of the three antibiotics, metronidazole, clarithromycin or amoxicillin, are added to a proton pump inhibitor or ranitidine bismuth citrate. Because of the rising incidence of primary and secondary antimicrobial resistance, especially to metronidazole and clarithromycin, the therapeutic success must be confirmed. 13C urea breath test is the diagnostic test of choice. In the case of treatment failure, new antimicrobial combinations are prescribed according to the therapeutic guidelines or the results of Helicobacter pylori culture and susceptibility testing. Up to 10% of patients cannot be cured of Helicobacter pylori infection. A hope for them is a therapeutic vaccine, which, unfortunately, will not become a reality soon.
Deskriptorji		STOMACH ULCER DUODENAL ULCER ANTIBIOTICS HELICOBACTER PYLORI