Avtor/Urednik		Banič, S; Koren, S; Tomažič, J; Vidmar, L; Ihan, A; Poljak, M; Avšič-Županc, T
Naslov		Influenza vaccination of human immunodeficiency virus 1-infected patients receiving antiretroviral therapy
Tip		članek
Vir		Acta Virol
Vol. in št.		Letnik 45
Leto izdaje		2001
Obseg		str. 39-44
Jezik		eng
Abstrakt		In 13 human immunodeficiency virus 1 (HIV-1) infected patients receiving a highly active antiretroviral therapy (HAART) annual influenza vaccination was conducted. It was hoped that HAART would prevent a post-vaccination increase in HIV-1 load and potential adverse effects. Only two patients had an increased viral load on day 14 post vaccination (p.v.) At 6 months p.v., the majority of the patients had a significantly increased CD4 cell count and a significantly decreased viral load. This indicates that HAART can protect patients from adverse consequences of influenza vaccination. The production of antibodies to the influenza A and B viruses in the HIV-infected patients was substantially lower than in healthy persons. We propose that HIV-positive patients receiving HAART should be subjected to annual influenza vaccination.
Deskriptorji		ACQUIRED IMMUNODEFICIENCY SYNDROME INFLUENZA VACCINE HIV-1 FLOW CYTOMETRY POLYMERASE CHAIN REACTION RNA, VIRAL CD4 LYMPHOCYTE COUNT IGG ANTIBODIES, VIRAL INFLUENZA A VIRUS INFLUENZA B VIRUS