Avtor/Urednik     Vlaisavljević, V; Kovačič, B; Gavrič-Lovrec, V; Reljič, M
Naslov     Simplification of the clinical phase of IVF and ICSI treatment in programmed cycles
Tip     članek
Vir     Int J Gynecol Pathol
Vol. in št.     Letnik 69, št. 2
Leto izdaje     2000
Obseg     str. 135-42
Jezik     eng
Abstrakt     Objective: To evaluate the success of a protocol for controlled ovarian hyperstimulation allowing patient self-selection into groups for ovulation stimulation planned 8 weeks and more in advance following rycle synchronization, drug self-administration as well as a reduced number of folliculometries. Methods: A total of 714 patients received the same stimulation protocol. In 260 cases GaRH-a was applied daily and in 454 as depot. In all patients FSH-HP was self-administered subcutaneously for ovarian stimulation. In 316 patients IVF and in 398 patients ICSI was performed. Results: The delivery rate per started cycle was higher in patients receiving depot GnRH-a in the IVF and ICSI group (30.2 vs. 23.4) than in those receiving subcutaneous GnRH-a (20.2 vs. 22.1). Conclusion: Programming of the IVF/ICSI cycle greatly simplifies treatment. A comparison of pregnancy rate and delivery rate per cycle between depot and subcutaneous daily application of GnRh-a did not confirm any statistically significant difference.
Deskriptorji     FERTILIZATION IN VITRO
OVULATION INDUCTION
OOCYTES
OVARIAN HYPERSTIMULATION SYNDROME
GONADORELIN
PREGNANCY
TREATMENT OUTCOME