Avtor/Urednik		Gurfinkel, Enrique P
Naslov		Antithrombotic therapy in acute coronary syndromes
Tip		članek
Vir		In: Štiblar-Martinčič D, Petrovič D, editors. Cardiovascular diseases. Proceedings of the 32nd memorial meeting devoted to professor Janez Plečnik, International symposium in memory of professor Rene Favaloro; 2001 Dec 6-8; Ljubljana. Ljubljana: Medical faculty,
Leto izdaje		2001
Obseg		str. 167-71
Jezik		eng
Abstrakt		The classification of unstable angina has, until now, been based on simple clinical descriptors, such as whether the ischaemic pain is on exertion and accelerating, or whether it occurs at rest, and whether or not ischaemia persists despite vigourous anti-ischaemic therapy. The ECG, particularly the presence or absence of changes in the ST segment, has also been useful as a classification tool. In addition, markers of myocardial damage, such as the cardiacspecific troponins -T or -I are being used increasingly in the classification of these patients. Such clinical and laboratory descriptors are valuable in predicting prognosis, but they provide little or no information about the aetiology of unstable angina. Such information is important because it allows specific rather than empiric management. Defining the aetiology of unstable angina is likely to become as important in selecting management options in the future as determining the severity and estimating the prognosis are at present. Methods to define the aetiology of unstable angina in individual patients are becoming more widely available. Accurate determination of the cause of this syndrome will allow individualized treatment which may be expected to improve clinical outcome.
Deskriptorji		CORONARY DISEASE FIBRINOLYTIC AGENTS ANGINA, UNSTABLE ELECTROCARDIOGRAPHY BIOLOGICAL MARKERS PROGNOSIS TROPONIN C-REACTIVE PROTEIN ANTITHROMBINS