Avtor/Urednik		Bergant, Damijan
Naslov		Medularni rak štitnjače u Sloveniji u razdoblju od 1969. do 1995. godine
Tip		monografija
Kraj izdaje		Zagreb
Založnik		Sveučilište u Zagrebu Medicinski fakultet
Leto izdaje		2001
Obseg		str. 57
Jezik		cro
Abstrakt		The data of Cancer Registry of Slovenia report of 1225 thyroid cancer cases detected in Slovenia during the period 1969-1995. Our 60 patients with MTC represent 4.9%. They were all diagnosed and/or treated at the Institute of Oncology, Ljubljana, with the exception of 18.3% of patients, who received primary treatment in other medical centers. The age of patients at the time of the first visit ranged between 16 and 81 years (44.6+-15.5). The study included 27 males, aged 16-77 years (45+-15.2) and 33 females, aged 16-81 years (44+-16.0) and M : F ratio was 1:1.2. The observation period was completed on 31 December 1999. The follow-up ranged from 2-372 months with the median follow-up 91 months. According to TNM classification, 2 patients had MTC stage 1, 17 stage 2, 28 stage 3 and 13 stage 4. The study group comprised 13.3*fo of the patients, aged between 16 and 57 years (29.4+-4.6), with the inherited MTC. MEN 2A, MEN 2B and FMCT were diagnosed in 3, 2 and 3 patients, respectively. We also present one of our patients with MTC, gigantic habitus and epiphysiolysis. During the follow-up, we diagnosed ectopic ACTH syndrome as a result of MTC hepatic metastases in 3 patients. Metastases from MTC were detected in the pericardium and on the wall of the ovarian cyst in 2 cases. Patients, in whom TC and CEA were determined before treatment, had all pathologically elevated TC values and also CEA values in 97,7%. FNAB, which was performed in 93.3% of patients, detected MTC in 87.5%. DMSA and MIBG scintigraphy was carried out on 61.7% of patients. We found true-positive accumulations of DMSA and MIBG in 67.6% and 29.8% of cases, respectively. (Abstract truncated at 2000 characters)
Deskriptorji		THYROID NEOPLASMS CARCINOMA, MEDULLARY NEOPLASM STAGING SURVIVAL ANALYSIS SLOVENIA