Avtor/Urednik		Ostrouška, M; Rostaher, A; Pečar, J; Seliškar, A; Butinar, J
Naslov		Vrednotenje analgetičnih učinkov nesteroidnega analgetika karprofena v med in pooperacijskem obdobju pri psih
Prevedeni naslov		Evaluation of the analgesic effects of nonsteroidal entiinflamatory drug carprofen in intra and postoperative period in dogs
Tip		članek
Vir		In: Vintar N, Lopuh M, editors. Zbornik predavanj 3. slovenski kongres anesteziologov Slovenije z mednarodno udeležbo; 2001 okt 11-13; Bled. Ljubljana: Slovensko zdravniško društvo, Slovensko združenje za anesteziologijo in intenzivno medicino,
Leto izdaje		2001
Obseg		str. 394-404
Jezik		slo
Abstrakt		Background. The aim of the research was to evaluate the analgesic effects of carprofen in intra and postoperative period in healthy dogs which undergone ovariectomy. Methods. The research was carried out on 16 healthy female dogs of different breeds undergoing ovariectomy. Dogs were assigned randomly to one of two groups. First group of dogs was premedicated with medetomidine 1000microg/m2 i:m., and the second one with medetomidine 1000microg/m2 i.m. and carprofen 4 mg/kg i.m., respectively. Dogs were induced with propofol 1 mg/kg i.v. Anaesthesia was maintained with isoflurane in 100% oxygen (FEIso 1%, Fi02 1.0). Intraoperative analgesia was assesed regarding changes in heart rate, arterial blood pressure, respiratory rate, minute ventilation and spontaneous movements. Postoperative analgesia was assesed with a modified numerical scale and regarding changes in heart and respiratory rate. Results. Dogs given carprofen had lower heart rate, respiratory rate and mean arterial blood pressure during the surgery comparing to the other group of dogs. Heart rate was significantly lower in 4. phase (pulling the left ovarial ligament; p = 0.05) in dogs premedicated with carprofen. The same dogs had significantly lower respiratory rate in 8. phase (skin suturing; p = 0.037) and significantly lower mean arterial blood pressure in 1. (basal measurements; p = 0.007),, 2. (skin incision; p = 0.019) and 3. (incision of peritoneum; p = 0.011) phase of experiment. Postoperative analgesia was insignificantly better in dogs given carprofen. Conclusions. Carprofen 4 mg/kg i.m preoperatively improves intraoperative analgesia and gives adequate postoperative analgesia for at least six hours after the surgery.
Deskriptorji		ANALGESIA INTRAOPERATIVE PERIOD POSTOPERATIVE PERIOD ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL HEART RATE PULSE BLOOD PRESSURE DOGS