Avtor/Urednik | Anžič, B; Čopar, A; Kuzman, T; Šolmajer, T | |
Naslov | Sinteza potencialno biološko učinkovitih tribaktamskih inhibitorjev beta-laktamaz | |
Tip | članek | |
Vir | In: Glavič P, Brodnjak-Vončina D, editors. Zbornik referatov s posvetovanja Slovenski kemijski dnevi 1998; 1998 sep 17-18; Maribor. Maribor: FKTT, | |
Leto izdaje | 1998 | |
Obseg | str. 220-5 | |
Jezik | slo | |
Abstrakt | Carbapenem systems with inhibitory activity towards the p-lactamases known up to now, are bicyclic compounds. Synthesis of new, potentially biological active tricyclic derivatives of carbapenems was designed on the basis of theoretical computer methods and molecular modelling. The synthesis of the tricyclic system is described and the results of biological tests of the basic system and of some derivatives are presented. | |
Deskriptorji | DRUG INDUSTRY CARBAPENEMS BETA-LACTAMASES |