Avtor/Urednik     Anžič, B; Čopar, A; Kuzman, T; Šolmajer, T
Naslov     Sinteza potencialno biološko učinkovitih tribaktamskih inhibitorjev beta-laktamaz
Tip     članek
Vir     In: Glavič P, Brodnjak-Vončina D, editors. Zbornik referatov s posvetovanja Slovenski kemijski dnevi 1998; 1998 sep 17-18; Maribor. Maribor: FKTT,
Leto izdaje     1998
Obseg     str. 220-5
Jezik     slo
Abstrakt     Carbapenem systems with inhibitory activity towards the p-lactamases known up to now, are bicyclic compounds. Synthesis of new, potentially biological active tricyclic derivatives of carbapenems was designed on the basis of theoretical computer methods and molecular modelling. The synthesis of the tricyclic system is described and the results of biological tests of the basic system and of some derivatives are presented.
Deskriptorji     DRUG INDUSTRY
CARBAPENEMS
BETA-LACTAMASES