Avtor/Urednik		Kuzmanović, Biljana; Henč-Petrinović, Ljerka; Sobol, Zlatko; Petrinović-Dorešić, Jelena
Naslov		Echographic picture of optic nerve glioma in neurofibromatosis type-1
Prevedeni naslov		Ehografska slika glioma vidnega živca pri nevrofibromatozi tip 1
Tip		članek
Vir		Zdrav Vestn
Vol. in št.		Letnik 71, št. Suppl 2
Leto izdaje		2002
Obseg		str. II-79-81
Jezik		eng
Abstrakt		Background. Authors want to present echographic picture of orbital part of low-grade pilocytic astrocytoma involving the optic nerve and/or chiasm and optic tract (optic pathway glioma or visual pathway glioma). Methods. 4 children with neurofibromatosis type-1 complicated with optic pathway glioma diagnosed earlier with magnetic resonance were examined by ultrasound. Standardised A scan technique was used for optic nerve width measurement The 30 degrees test and B-scan (axial, transverse and longitudinal sections) of both eyes and orbits were performed as well. Results. The optic nerve diameter in our cases ranged from 4.48 to 85 mm. Two children had the left side optic pathway glioma, one boy had the right side optic pathway glioma and in one tumour was bilateral. The transversal section of the nerve revealed dark oval and in moreperpendicularsections round void of the nerve. As the beam is swept towards the orbital apex void becomes more fusiform. The nerve and its sheaths are markedly widened. An abnormal increase in reflectivity and irregularity of the spike's pattern is exhibited as well. No calcification along the sheaths is noticed. The transverse section of the tumour demonstrated an "inverse doughnut" sign. The outer whiter outline of the widened sheaths surrounds an inner darker circle. The longitudinal section revealed the optic nerve head continuing into the widened optic nerve. The 30 degrees test was negative. The differential diagnosis of meningeoma, optic neuritis and orbital cysticercosis should be considered. Conclusions. Ultrasound as a cheap, safe, easily repeatable imaging method should become a method of choice fors creening optic nerve tumours in neurofibromatosis type-1, especially in children, as well as for follow-up after treatment.
Izvleček		Izhodišča. Avtorji želijo predstaviti ehografsko sliko orbitalnega dela nizko razvojnega pilocitičnega astrocitoma, ki vključuje vidni živec in/ali hiazemo in očesni trakt (gliom optične poti oziroma gliom vidne poti). Metode. Z ultrazvokom so pregledali štiri otroke z nevrofibromatozo tip-1 z dodatno komplikacijo glioma očesne poti, ki je bil pred tem diagnosticiran z magnetno resonanco. Za merjenje širine vidnega živca so uporabili standardizirano tehniko A-scan. Prav tako so opravili 30 stopnijski test in B-scan (osni, prečni in vzdolžni prerez) obeh očes in očesne votline. Rezultati. Premer vidnega živca je segal od 4,48 do 8,5 mm. Otroka sta imela gliom leve strani optične poti, en deček je imel gliom desne strani optične poti, v enem primeru pa je bil tumor obojestranski. Prečni prerez živca je odkril temno ovalno vrzel živca, pravokotni prerez pa okroglo vrzel živca. Z usmeritvijo žarka proti vrhu očesne votline je postala vrzel bolj vretenasta. Živec in njegove ovojnice so postale izrazito razširjene. Prav tako je bilo razvidno tudi nenormalno povečanje pri reflektivnosti in nepravilnosti vzorca. Vzdolž ovojnic ni bilo zaznavne kalcifikacije. Prečni prerez tumorja je kazal znak "obrnjenega krofa". Zunanji belkasti obris razširjene ovojnice je obkrožal notranji temnejši krog. Vzdolžni prerez je razkrival nadaljevanje glave vidnega živca v razširjeni vidni živec. 30 stopinjski test je bil negativen. Potrebno je upoštevati diferencialno diagnozo meningoma, vnetje vidnega živca in cisticerkozo očesne votline. Zaključki. Ultrazvok kot poceni, varna in lahko ponovljiva metoda slikanja bi morala postati metoda prvega izbora za presejanje tumorjev vidnega živca pri nevrofibromatozi tip-1, posebno pri otrocih, kakor tudi za opazovanje po zdravljenju.
Deskriptorji		OPTIC NERVE DISEASES GLIOMA NEUROFIBROMATOSIS 1