Avtor/Urednik		Blinc-Pesek, Marjeta
Naslov		Družinsko pojavljanje shizofrenije - značilnosti staršev in njihovih potomcev, obolelih za shizofrenijo
Tip		monografija
Kraj izdaje		Ljubljana
Založnik		Medicinska fakulteta
Leto izdaje		2002
Obseg		str. 38
Jezik		slo
Abstrakt		It is known that schizophrenia aggregates strongly in families. First degree relatives of schizophrenic patients have a 5 to 10 times higher risk for schizophrenia than poeple with no schizophrenia in their family. The etiology of schizophrenia is not yet completely known. Most researchers agree that both genetic and environmental factors and their interactions are important in the etiology and fenotipic expression of the disease. Anticipation, decreasing age of onset and increasing disease severity, has been confirmed in many epidemiological studies of schizophrenia. The phenomenon has its molecular basis in trinucleotide repeat expansions and it has been proved for many neurodegenerative diseas, but not yet for schizophrenia. The aim of our study is to evaluate the epidemiological phenomenon of anticipation in our sample of schizophrenic parents and their children. All of them were treated at the Ljubljana Psychiatric Hospital. Our sample consists of 36 parent-offspring pairs of schizophrenic patients. The demographic characteristics of the sample were described (their sex and age in the year 2000). The groups (parents and offspring) were compared by some of their social characteristics (marital state, level of education, employment, number of children), age at disease onset and some indirect indicators of disease severity (total number of days in hospital during the first five years of treatment, total number of hospitalizations). The data was collected from the disease files that are kept in the archive of the Ljubljana Psihiatric Hospital. The patients included in our sample were diagnostically classified as schizophrenic or schizoaffective. The ICD 10 diagnostic criteria were used. (Abstract truncated at 2000 characters).
Deskriptorji		SCHIZOPHRENIA SOCIOECONOMIC FACTORS HOSPITALIZATION LENGTH OF STAY AGE OF ONSET FAMILY SUICIDE, ATTEMPTED