Avtor/Urednik		Kornhauser-Cerar, Lilijana; Babnik, Janez; Pestevšek, Maja
Naslov		Mejna viabilnost - zgodnji izid pri nedonošenčkih rojenih pred 26. tednom nosečnosti
Prevedeni naslov		The limit of viability - early outcome of infants born before 26 weeks' gestation
Tip		članek
Vir		In: Novak-Antolič Ž, editor. Klinično upravljanje strokovnosti v perinatologiji. Zbornik prispevkov 10. Novakovi dnevi z mednarodno udeležbo; 2002 maj 30-jun 1; Bled. Ljubljana: Slovensko zdravniško društvo, Združenje za perinatalno medicino,
Leto izdaje		2002
Obseg		str. 44-53
Jezik		slo
Abstrakt		Background. To established the value of " transport in utero" in early pregnancy we conducted a survey on the mortality and morbidity rates of infants with gestational ages of less than 26 weeks. Methods. We studied retrospectivelly the data on 128 infants born at 22 to 25 weeks gestation in Maternity Hospital Ljubljana in the four-year period of 1997 to 2000. Mortality in the first three months (until discharge), including stillbirths, and morbidity were analyzed. Results. There were 52 stillbirths (41%): 10 at 22 weeks of gestation, 13 at 23, 16 at 24, and 13 at 25 weeks of gestation. 76 out of 128 infants were liveborn; 32 of them (42.1%) survived until discharge from the hospital. Survival improved with increasing gestational age; none of the 14 infants born at 22 weeks gestation survived, as compared with 2 of 12 (16.7%) born at 23 weeks, 11 of 21 (52.4%) born at 24 weeks, and 19 of 29 (65.5%) born at 25 weeks. Nearly half (48.7%) of live-borns died within 1 week after birth and only two (2.6%) died after the neonatal period. The main causes of death were: severe prematurity (in 68%), congenital malformations (11%), intracranial hemorrhage grade III-IV (9%), acute respiratory failure (7%), infection (2%), and hypoxia(2%). Morbidity was analyzed only for those who have survived for 24 hours or more. In the majority of infants who have died in the first hours after birth, extreme immaturity was marked as the cause of the death; as their life was to short that the signs of specific diseases could develop, their incidence would be falsely low. Hyaline membrane disease was found in 80%, bronchopulmonary dysplasia in 54%, persistent ductus arteriosus in 56%, and sepsis in 21%. Ultrasonographycally, periventricular or severe intraventricular hemorrhage was found in 28%, and signs of periventricular leukomalacia in 5%. Retinopathy of prematurity was diagnosed only in 3 infants (8%). (Abstract truncated at 2000 characters).
Deskriptorji		INFANT, VERY LOW BIRTH WEIGHT INFANT MORTALITY FETAL VIABILITY INFANT, PREMATURE RESUSCITATION RETROSPECTIVE STUDIES INFANT, NEWBORN INFANT GESTATIONAL AGE INFANT, PREMATURE, DISEASES APGAR SCORE