Avtor/Urednik		Matos, Tadeja
Naslov		Ekologija glive Exophiala dermatitidis in filogenetski odnos nevrotropnih črnih kvasovk in njihovih sorodnikov
Tip		monografija
Kraj izdaje		Ljubljana
Založnik		Medicinska fakulteta
Leto izdaje		2002
Obseg		str. 91
Jezik		slo
Abstrakt		Fungal infections of the central nervous system are extremely rare, but may have been overlooked due to inadequate diagnostics. The route of infection is as yet unknown. In most cases such infections seem to be a consequence of hematogenous dissemination by opportunistic fungi. In other cases the infection spreads directly to cerebral tissue by the breaking in from nasal-gorge area. In the Ascomycete family Herpotrichiellaceae three species of dark-pigmented fungi are known, which can cause primary infection of a central nervous system in patients with normal immune response. Symptoms of infection in all three species are a consequence of the presence of solitary or multiple abscesses in cerebral tissue. Increased intracranial pressure and focal neurological seizures are often observed. In most cases, the course of infection is acute with bad prognosis of illness, as current therapeutic measures are often unsuccessful. Up to the present, Ramichloridium mackenziei was isolated exclusively from cerebral tissue of patients. These had one characteristic in common: all were originating from the Middle East. The sporadic cases of infections of central nervous system caused by Cladophialophora bantiana can be found all over the world. Neurotropic infections caused by the black yeast Exophiala dermatitidis are geographically restricted to Japan and neighbouring countries. In this research we tried to explain the uneven distribution of central nervous system infections by E. dermatitidis, by applying molecular-epidemiological methods and selective isolation. In the first part of our research we searched for the preferred ecological ecological niche of E. dermatitidis in Europe using systematic sampling from a diversity of environments which we suspected as possible habitats on the basis of epidemiological and physiological parameters such as thermotolerance. Some of these are part of the human environment and could represent the source of infection. (Abstract tr
Deskriptorji		EXOPHIALA FOOD MICROBIOLOGY SOIL MICROBIOLOGY ENVIRONMENTAL MICROBIOLOGY FECES FRUIT PHYLOGENY YEASTS GENOTYPE POLYMERASE CHAIN REACTION CENTRAL NERVOUS SYSTEM DISEASES