Avtor/Urednik     Rozman, Janez; Zorko, Bojan; Bunc, Matjaž; Mikac, Urša; Tegou, Evangelia
Naslov     Recording of ENGs from the nerves innervating the pancreas of a dog during the intravenous glucose tolerance test
Tip     članek
Vir     Physiol Meas
Vol. in št.     Letnik 23
Leto izdaje     2002
Obseg     str. 695-705
Jezik     eng
Abstrakt     Electroneurograms (ENGs) from the vagus nerve (VN), the splanchnic nerve (SN) and the pancreatic nerve (PN) innervating the pancreas of a dog, were recorded with chronically implanted 33-electrode spiral cuffs (cuff) before and after the pancreas were stimulated with intravenously (i.v.) administered glucose. In the cuffs platinum electrodes were arranged in three parallel spiral groups containing 11 electrodes on the inner surface. The cuffs had an inner diameter of 2 mm and the length of 18 mm. In a two-year study, the cuffs were implanted into two Beagle dogs and were also used for pancreatic stimulation, although this is not described in this paper. In the VN, the cuff was installed on the nerve at the neck, whilst in the SN, the cuff was installed on the nerve before the celiac ganglion, and in the PN, the cuff was installed on the nerve just before it enters the pancreas. Six months after implantation, when the model of interpretation of the results was developed, three recordings of ENG in each animal were conducted. The first one was conducted in the unstimulated pancreas while the second and the third were conducted 1 and 8 min after a known amount of glucose was i.v. administered. Since the results obtained in both animals were actually quite similar, we present the results obtained in one animal. To evaluate the changes in superficial activity of the nerves, elicited by the administration of glucose, the power spectra corresponding to ENGs, recorded from the nerves before and after the administration of glucose, were integrated within the band of frequencies ranging from 1 to 5 kHz. Accordingly, the magnitude of the integrated power spectrum (MIPS), corresponding to the ENG recorded from the SN before administration of glucose, was 2.863 a.u. (Abstract truncated at 2000 characters).
Deskriptorji     GLUCOSE TOLERANCE TEST
PANCREAS
ELECTRIC STIMULATION
ELECTRODES, IMPLANTED
DOGS
ACTION POTENTIALS