Avtor/Urednik     Rocquet, C; Bonte, F
Naslov     Molecular aspects of skin ageing: recent data
Tip     članek
Vir     Acta Dermatovenerol Alp Pannon Adriat
Vol. in št.     Letnik 11, št. 3
Leto izdaje     2002
Obseg     str. 71-94
Jezik     eng
Abstrakt     As our body's envelope, the skin acts as a biosensor with the environment and reflects our personality. Skin ageing is therefore an important and interesting topic of study. It results from the combination of intrinsic ageing and photoageing, which is due to the environmental influence, such as reactive oxygen species (ROS). The more recent data are gathered here to remind current knowledge about skin ageing, from a molecular level to the clinical signs, wrinkles and spots mainly. Because knowledge of the preferential biological targets of ageing has recently been making progress, it is possible to delay the manifestation of ageing, by acting on key biological processes.
Deskriptorji     SKIN AGING
DNA DAMAGE
REACTIVE OXYGEN SPECIES
DNA, MITOCHONDRIAL
PROTEINS
OXIDATIVE STRESS
PROTEASE INHIBITORS
GLYCOSYLATION END PRODUCTS, ADVANCED
METALLOPROTEINASES
TELOMERASE