Avtor/Urednik     Syrjanen, Kari; Eržen, Mojca
Naslov     Sertoli-Leydig cell tumours of the ovary - implications of histological subtypes
Tip     članek
Vir     CME J Gynecol Oncol
Vol. in št.     Letnik 7, št. 2
Leto izdaje     2002
Obseg     str. 145-63
Jezik     eng
Abstrakt     Sertoli-Leydig cell tumours of the ovary comprise a special group of tumours derived from the sex cord and stromal elements. This group is generally referred to as Sertoli-stromal cell tumours, comprising the lesions derived from the Sertoli cells, cells resembling rete epithelial cells, and pure Leydig cells. These tumours can occur either in pure form or as mixtures of any of these three cell types. According to the current WHO classification, Sertoli-Leydig cell tumours are grouped under two main categories of ovarian tumours: 1. sex cord-stromal tumours and 2. steroid cell tumours. Within both two categories, a number of subtypes are differentiated, each, presenting with special clinical and histopathological characteristics. The present communication gives an overview on these different subtypes of Sertoli-Leydig cell tumours included both in the sex cord-stromal tumour and steroid cell tumour categories. In addition to giving definitions to all these lesions, special emphasis is focused on presenting the essential data on their 1. histogenesis, 2. clinical presentation (briefly), 3. gross appearance, 4. microscopic patterns, 5. ultrastructure, and, where pertinent, 6. immunohistochemical findings. The text is supplemented with ' a set of colour micrographs, demonstrating the representative light microscopic characteristics of Sertoli-Leydig cell tumours collected from the archives of one of the authors (ME). In addition to including the core references of the classical texts addressing these lesions, the authors performed an extensive Medline search (Abstract truncated at 2000 characters)
Deskriptorji     OVARIAN NEOPLASMS
SEX CORD-STROMAL TUMOR
SERTOLI-LEYDIG CELL TUMOR
SERTOLI CELL TUMOR
LEYDIG CELL TUMOR
NEOPLASMS, GONADAL TISSUE
DIAGNOSIS, DIFFERENTIAL
WORLD HEALTH ORGANIZATION