Avtor/Urednik		Aigner, Reingard M; Schultes, Guenter; Wolf, Gerald; Schwarz, Thomas; Lorbach, Mark
Naslov		F-18-FDG PET in presurgical oro-maxillofacial carcinomas
Prevedeni naslov		Diagnostičen pomen F-18-FDG PET pri oro-maksilofacialnih malignomih pred kirurškim zdravljenjem
Tip		članek
Vir		Radiol Oncol
Vol. in št.		Letnik 36, št. 4
Leto izdaje		2002
Obseg		str. 327-9
Jezik		eng
Abstrakt		Background. We performed an analysis of the diagnostic impact of F-18-FDG-PET in presurgical oro-maxillofacial malignancies. Patients and methods. The diagnosis of the malignant primary was made clinically and was histological- ly verified before FDGPET and the cervical CT examinations were performed in 25 patients of this study. For the FDG-PET investigation a full ring PET scanner was used (ECAT EXACT HR+, Siemens). Thoracic CT was performed only if pathological findings on FDG-PET scans required it. Results. The primary was clearly identified with FDG-PET in all patients. Active cervical lymph node sites were seen in 9/25 patients (ipsilateral: 8/25; ipsi- and contralateral: 1/25). Lung-metastases were found in 2/25 patients. Cervical CT: The primary was recognised in all patients. Artefacts caused by dental implants did not allow visualising the extension of the tumour in 9/25 patients. Ipsilateral lymph node sites were seen in 7/25 patients (size: 0.9-1.6 cm), and ipsiand contralateral lymph node sites in 7/25 patients (size: 0.8-1.8 cm). The lung metastases primarily recognised with FDG were visualised with CT in both patients, too. Conclusion. FDG-PET is a sensitive diagnostic modality for the preoperative visualisation of active, i.e. suspicious malignant lymph nodes. Distant metastases were demonstrated in 8% of the patients on whole body PET. The usefulness of FDG-PET and CT for establishing the diagnosis of the primary is limited. The preoperative importance of CT lies primarily in the accessibility of the algorithms for the intraoperative recon- struction of the facial structures.
Izvleček		Izhodišča. Analizirali smo diagnostični pomen FDG-PET pri oro-maksilofacialnih malignomih pred kirurškim zdravljenjem. Bolniki in metode. Pri 25 bolnikih, vključenih v študijo, smo klinično in histološko potrdili primarni maligni tumor še preden smo opravili FDG-PET in cervikalni CT. Pri FDG-PET smo uporabili krožni PET čitalnik (ECAT EXACT HR+, Siemens). CT prsnih organov smo opravili samo pri tistih bolnikih, kjer je FDG-PET pokazal patološke spremembe. Rezultati. Primarni tumor smo s FDG-PET identificirali pri vseh bolnikih. Pri 9/25 bolnikih smo prikazali aktivne vratne bezgavke (ipsilateralne 8/25; ipsi- in kontralateralnel/25). Pri 2/25 bolnikih smo našli pljučne metastaze. Prav tako smo s cervikalnim CT-jem identificirali primarni tumor pri vseh bolnikih. Artefakti povzročeni z zobnimi vsadki so preprečili prikaz razširjenosti tumorja pri 9/25 bolnikih. Ipsilateralne bezgavke smo prikazali pri 7/25 bolnikih (velikosti 0,9- 1,6 cm), ipsi- in kontralateralne bezgavke pa pri 7/25 bolnikih (velikost 0,8-1,8 cm). Pljučne zasevke prikazane s FDG smo prikazali tudi s CT-jem pri obeh bolnikih. Zaključki. FDG-PET je občutljiva diagnostična metoda za preoperativni prikaz aktivnih, torej sumljivih bezgavk. Oddaljene zasevke smo dokazaki pri 8 % bolnikov, ko smo naredili PET celega telesa. Uporabnost FDG-PET in CT-ja za postavljanje diagnoze primarnega tumorja je ome- jena. Preoperativni CT nam je v veliko pomoč predvsem za določanje algoritmov, potrebnih pri intraoperativni rekonstrukciji obraznih struktur.
Deskriptorji		MAXILLARY NEOPLASMS MOUTH NEOPLASMS TOMOGRAPHY, X-RAY COMPUTED TOMOGRAPHY, EMISSION-COMPUTED FLUORINE RADIOISOTOPES