Avtor/Urednik		Bitenc, Marko
Naslov		Vpliv diagnostične mediastinotomije na nastanek citološko pozitivnega plevralnega eksudata pri bolnikih s karcinomom pljuč
Tip		monografija
Kraj izdaje		Zagreb
Založnik		Sveučilište u Zagrebu, Medicinski fakultet
Leto izdaje		1992
Obseg		str. 50
Jezik		cro
Abstrakt		In the study the influence of diagnostic mediastinotomy on the development of citologically positive pleural exudate in patients with carcinoma of the lung is evaluated. The study envelops 188 patients who were treated for lung cancer at the University Clinic for Thoracic Surgery in Ljubljana from 1986 to 1987. The evaluation was made in 181 patients who underwent thoracotomy. Seven of those 188 patients had to be exempted of thoracotomy because of the fmdings of the preoperative staging. With statistic analyses ( hi-square test, Kaplan-Meier method of survival rate, Mantel-Cox test for the comparison of survival curves) the group of patients, who were mediastinotomized in the course of preoperative staging, was compared with the group that was not mediastinotomized. The study shows that preoperative mediastinotomy provokes the development of pleural exudate, of which the sample was never citologically positive. Some samples of pleural exudates in patients in whom preoperative mediastinotomy was performed were citologically suspicious. The fact that the fmdings of those patients were in fact negative is confirmed by the survival of those patients which is not shorter than the survival of patients with negative citological findings. The results of the study show that preoperative mediastinotomy in patients with the lung cancer, if con:ectly indicated, is an advantageous diagnostic method, for it reduces the number of undesirable explorative thoracotomies. At the same time it has no negative effects on the survival of these patients. Since in mediastionotomized patients the selection for operability is subjected to stricter criteria, it can be said that the patients who were determined for surgery also by this diagnostic method, have better expectancy for survival.
Deskriptorji		LUNG NEOPLASMS MEDIASTINUM POSTOPERATIVE COMPLICATIONS PLEURAL EFFUSION, MALIGNANT NEOPLASM STAGING