Avtor/Urednik		Skerbinjek-Kavalar, M; Homšak, M; Brunčko, A
Naslov		Kožne spremembe pri otrocih s prehransko alergijo
Prevedeni naslov		Skin symptoms of food-allergic children
Tip		članek
Vir		In: Gregorič A, editor. Nutritivna alergija. Farmakologija perinatalnega obdobja. Skrb za zdravje v prvem letu življenja. Zbornik predavanj 13. srečanje pediatrov v Mariboru z mednarodno udeležbo; 2003 apr 4-5; Maribor. Maribor: Splošna bolnišnica Maribor,
Leto izdaje		2003
Obseg		str. 60-3
Jezik		slo
Abstrakt		Adverse food reaction is the general term referring to any aberrant reaction following the ingestion of a food or food additive. Adverse food reactions could be the result of »food allergy« - hypersensitivity or food intolerance. Food allergic reaction are considered to be the result of an abnormal immunological response following the ingestion of a food, whereas food intolerances are the consequence of nonimmunological mechanisms (1,2,3). Adverse food reactions are more common in children, especially in the first year of life. Epidemiological studies suggests that about 1,5-2% of the population is affected by food reactions, 8,5% of children in the first year of life. About 20% of children with atopic dermatitis (AD) have immunological food reactions. The main allergens are cow's milk, egg, peanut, cocoa and sea food. Food allergy in young children should probably be considered one component of an »allergic quadrad« and we recognize a familiar pattern of inheritance (4). Many defects of the cellular immune system have been described in AD, the main is an increased ratio of CD4+ T cells to CD8+ cells, the abnormal cytokine expression and abnormal expression of adhesion molecules. The clinical signs and symptoms of AD differ according to the period of life, same as the therapy. Diagnostic test are unreliable. Bacterial and viral infections, stress, sweating, climate changes, psychological factors and some irritants are worsening the condition (5).
Deskriptorji		FOOD HYPERSENSITIVITY SKIN MANIFESTATIONS IMMUNITY, MUCOSAL CHILD URTICARIA ANGIONEUROTIC EDEMA DERMATITIS, ATOPIC