Avtor/Urednik | Blacher, Silvia; Devy, Laetitia; Noel, Agnes; Foidart, Jean-Michel | |
Naslov | Quantification of angiogenesis on the rat aortic ring assay | |
Tip | članek | |
Vir | Image Anal Stereol | |
Vol. in št. | Letnik 22, št. 1 | |
Leto izdaje | 2003 | |
Obseg | str. 43-8 | |
Jezik | eng | |
Abstrakt | Image analysis is used to quantify angiogenesis on the rat aortic ring model. This technique allows to determine: (1) the aortic ring area and factor shape; (2) the number of microvessels, the total number of branching, the maximal microvessel length and the number of microvessels in function of the distance to the aortic ring; (3) the total number of isolated fibroblast-like cells and the number of fibroblast-like cells in function of the distance to the aortic ring. We show that this method is suitable to quantify spontaneous angiogenesis as well as to analyse a complex microvascular network induced by vascular endothelial growth factor (VEGF). | |
Deskriptorji | AORTA FIBROBLASTS NEOVASCULARIZATION, PHYSIOLOGIC ENDOTHELIUM, VASCULAR IMAGE PROCESSING, COMPUTER-ASSISTED CELLS, CULTURED ENDOTHELIAL GROWTH FACTORS RATS |