Avtor/Urednik | Blacher, Silvia; Devy, Laetitia; Noel, Agnes; Foidart, Jean-Michel | |
Naslov | Quantification of angiogenesis in rat aortic ring assay | |
Tip | članek | |
Vir | Image Anal Stereol | |
Vol. in št. | Letnik 20, št. Suppl 1 | |
Leto izdaje | 2001 | |
Obseg | str. 123-8 | |
Jezik | eng | |
Abstrakt | lmage analysis is used to quantify angiogenesis on the rat aortic ring model. This technique allows to determine: (1) the aortic ring area and its factor shape; (2) the number of microvessels, the total number of branching, the maximal microvessel length and the microvessel distribution; (3) the total number of isolated fibroblast-like cells and their distribution. We show that this method is suitable to quantify spontaneous angiogenesis as well as to analyse a complex microvascular network induced by vascular endothelial growth factor (VEGF). | |
Deskriptorji | AORTA NEOVASCULARIZATION, PHYSIOLOGIC FIBROBLASTS IMAGE PROCESSING, COMPUTER-ASSISTED RATS, INBRED F344 CELLS, CULTURED |