Avtor/Urednik		Spindler-Vesel, A; Markovič, J; Potočnik, I; Šušteršič, J; Visočnik, B
Naslov		Remifentanil - based anaesthesia with propofol vs. isoflurane vs. sevoflurane in patients undergoing craniotomy for supratentorial space-occupying lesions
Tip		članek
Vir		In: Zabavnik Z, editor. Book of lectures of the 16th anaesthesia symposium Alpe Adria; 2003 May 9-11; Maribor. Maribor: Splošna bolnišnica,
Leto izdaje		2003
Obseg		str. 165-70
Jezik		eng
Abstrakt		Remifentanil - based anaesthesia provides complete awakening and orientation immediately after elective craniotomy. In prospective, randomised study recovery profiles of remifentanil - based anaesthesia with propofol, isoflurane and sevoflurane in small hypnotic concentrations have been compared. 60 patients (age 18-75 years, ASA physical status I, II or III) scheduled for elective excision of a supratentorial spaceoccupying lesion under general anaesthesia were enrolled in this study. Intraoperative consumption of remifentanil, propofol, vol % of isoflurane and sevoflurane were recorded. The time of the operation and the time from the end of the operation to the tracheal extubation were also noted. 5 minutes after tracheal extubation and again 30 min after extubation modified Aldrete score was recorded. Results showed that significatly less remifentanil was used in isoflurane - remifentanil group compared to propofol - remifentanil and sevoflurane - remifentanil groups. The time to extubation was significantly faster and the Aldrete score 5 minutes after extubation was significantly higher after propofol anaesthesia as compared to sevoflurane and isoflurane. No significant differences were found among groups in evaluation of Aldrete score 30 minutes after extubation. In our study recovery after remifentanil-based anaesthesia was faster with propofol than sevoflurane or isoflurane in patients undergoing craniotomy for supratentorial space-occupying lesion.
Deskriptorji		ANESTHESIA, GENERAL FENTANYL PROPOFOL ISOFLURANE CRANIOTOMY PROSPECTIVE STUDIES