Avtor/Urednik		Radan, Ivan; Urbančič-Rovan, Vilma; Možina, Martin; Bručan, Andrej
Naslov		Serotoninski sindrom - prikaz primera
Prevedeni naslov		Serotonin syndrome - case report
Tip		članek
Vir		In: Bručan A, Gričar M, Vajd R, editors. Urgentna medicina: izbrana poglavja. Zbornik 10. mednarodni simpozij o urgentni medicini; 2003 jun 11-14; Portorož. Ljubljana: Slovensko združenje za urgentno medicino,
Leto izdaje		2003
Obseg		str. 231-5
Jezik		slo
Abstrakt		The article describes a patient with clinical features of serotonine syndrome. A 35-yr-old woman was admitted following deliberate intoxication with tramadole, moclobemide (a monoaminooksigenase inhibitor), paroxetine (a selective serotonine reuptake inhibitor) and benzodiazepines. Upon admission she was unconscious, hyperthermic, diaphoretic with pronounced muscle rigidity. Toxicological analyses revealed the presenee of tramadol moclobemide and also paroxiten and zolpidem in smaller concentrations. After exclusion of other possible causes; serotonine syndrome was considered. Treatment was symptomatic with mechanical ventilation, sedation and neuromuscular block. The patient recovered spontaneously 24 hr later. Serotonine syndrome is characterized by varying degrees of cognitive, autonomic, and neuromuscular dysfunction and can only be triggered by drug therapy that increases central nervous system serotonin neurotransmission.
Deskriptorji		SUICIDE, ATTEMPTED SEROTONIN UPTAKE INHIBITORS MONOAMINE OXIDASE INHIBITORS BENZODIAZEPINES ADULT