Author/Editor		Ravnik-Oblak, M; Janež, A; Kocijančič, A
Title		Insulinoma induced hypoglycemia in a type 2 diabetic patient
Type		članek
Source		Wien Klin Wochenschr
Vol. and No.		Letnik 113, št. 9
Publication year		2001
Volume		str. 339-41
Language		eng
Abstract		Insulinoma in a patient with pre-existing diabetes mellitus is extremely rare. We report a case of an insulinoma in a patient with type 2 diabetes mellitus who after 14 years of sulfonylurea treatment experienced recurrent episodes of hypoglycemia. Endogenous hyperinsulinism was confirmed and endoscopic ultrasonography identified a pancreatic tumor, which was positive for insulin by immuno-histological staining. After surgical excision of the tumor, no further hypoglycemic attacks occurred. Loss of body weight after removal of the tumor correlated with a dramatic reduction of insulin resistance to such a degree that diet alone proved sufficient for satisfactory glycemic control.
Descriptors		PANCREATIC NEOPLASMS DIABETES MELLITUS, NON-INSULIN-DEPENDENT HYPERGLYCEMIA INSULINOMA AGED TREATMENT OUTCOME HYPERINSULINISM INSULIN RESISTANCE MEMORY DISORDERS PANCREAS