Author/Editor		Kokalj-Vokač, N; Canki-Klain, N; Debevec, M; Veble, A
Title		46,XX,inv(10)(p14q22)mat pri ženski s spontanimi splavi
Translated title		46,XX,inv(10)(p14q22)mat in a woman with spontaneous abortions
Type		članek
Source		Zdrav Vestn
Vol. and No.		Letnik 61, št. 2
Publication year		1992
Volume		str. 75-7
Language		slo
Abstract		Background: Most chromosome inversions are discovered by chance in examinations for sterility, abortions, still-births and malformations Method: The article presents a chromosome analysis from the culture of peripheral blood taken from a 28-year-old woman with three successive spontaneous abortions. Results: The chromosome analysis showed pericentric inversion in one of the chromosomes 10. A study of the patient's famity members established a similar chromosome anomaly in her mother. Conclusions: The pericentric inversion described can reduce the fertitity of bearers of this chromosome change, which probably causes the formation of a recombinative tie together with recombination and delection of such an extent that they prove fatal.
Descriptors		ABORTION, HABITUAL CHROMOSOME ABERRATIONS CHROMOSOMES, HUMAN, PAIR 10 PEDIGREE CYTOGENETICS