Author/Editor		Primožič, S
Title		Individualno doziranje zdravil v klasični in populacijski farmakokinetiki
Translated title		Dosage individualization in the classical and population pharmacokinetics
Type		članek
Source		Farm Vestn
Vol. and No.		Letnik 43, št. 1
Publication year		1992
Volume		str. 101-14
Language		slo
Abstract		The importance of dosage individualization in the modem therapeutics is increasing. Valid estimates of pharmacokinetic parameters are needed in the population and individual to perform dosage individualization. Classical and population pharmacokinetics offer in this respect two different approaches whose basic characteristics are outlined in this article. The classical approach rests on the basis of information obtained in rigorously planned clinical pharmacokinetic studies on a limited number of subjects. The population approach is based on concentration data collected loosely on a larger number of subjects as a part of their therapeutic program, and utilizes specific programming modeling tools.
Descriptors		PHARMACOKINETICS DRUG ADMINISTRATION SCHEDULE