| Author/Editor | Videnšek, J | |
| Title | Preprečitev nastajanja sekundarne katarakte po vstavitvi umetne očesne leče | |
| Type | monografija | |
| Place | Ljubljana | |
| Publisher | Medicinska fakulteta | |
| Publication year | 1992 | |
| Volume | str. 102 (152) | |
| Language | slo | |
| Abstract | Hemorrhagic Fever with Renal Syndrome (HFRS), caused by hantaviruses, is also present in Slovenia. To clarify the epizootiology of hantavirus infection, small mammals captured in natural foci of HFRS were studied. Data indicate a substantial evidence that the bank vole, Clethrionomys glareolus, and yellow-necked field mice, Apodemus flavicollis are the main hosts for hantaviruses in endemic areas in Slovenia. A hantavirus was isolated from lungs of an A. flavicollis captured in Dobrava village. In addition, two more hantavirus strains has been isolated from wild rodents and one from a fatal HFRS case. The isolate from A. flavicollis, designated Dobrava, was antigenicaly compared with viruses representative of each of known serogroups within the hantavirus genus. Based upon serological reactivity of monoclonal antibodies it was established that antigenic properties of Dobrava virus are different from other hantaviruses. RNA from all new isolates were reverse transcribed to cDNA and successfully amplified by polimerase chain reaction (PCR). The amplified products were digested with restriction endonucleases. Analyses of the restriction fragments indicate that Dobrava virus has a unique restriction pattern, therefore represent a new hantavirus type. The involvence of Dobrava virus in HFSR was studied by demonstrating specific antibodies in the serea from HFSR patients. It revealed that antibodies against Dobrava virus are present in HFSR patients. We presume that Dobrava virus is not the etiologic agent that causes severe forms of HFSR in Slovenia. -LEC metaplasia/fibrosis. Factors responsible for development of secondary cataract are: -Migration and proliferation of lens epithelial cells (LEC). -Remaining cortical material within the lens capsule. We routinely supressed the emergence of secondary cataract with antiflogistic therapy.(trunc.) | |
| Descriptors | LENSES, INTRAOCULAR CATARACT CATARACT EXTRACTION INDOMETHACIN CHYMOTRYPSIN INTRAOCULAR PRESSURE |