Author/Editor		Ribič, Helena; Smole, Alenka; Oražem, Toni
Title		Odpornost bakterij, ki smo jih osamili pri varovancih domov za ostarele
Translated title		Antibiotic resistance of bacteria isolated from nursing home residents
Type		članek
Source		Zdrav Vars
Vol. and No.		Letnik 42, št. 4
Publication year		2003
Volume		str. 145-56
Language		slo
Abstract		Background: The frequency of infections among nursing home residents is high. Many of these infections are caused by antibiotic-resistant bacteria and treating them reopresents an ever-increasing problem. The authors present the most frequently isolated bacterial species and their antibiotic sensitivity rates. The strains studied were isolated from specimens taken from nursing home residents in the Ljubljana region. Methods: In this retrospective study, bacterial strains, isolated from wounds and ulcers (196 strains) and from urine samples (555 strains), were analysed. Strain isolation and antibiotic sensitivity tests were done as part of the routine work of the microbiological laboratory of the national Institute of Public Health between January 2000 and December 2002. Results: Among bacterial strains isolated from urine samples, 12% of strains of enterobacteria were sensitive to ampicillin, 35% to co-amoxiclav, 32% to co-trimoxazole, 73% to gentamicin and 41% to norfloxacin; 51% of Pseudomonas aeruginosa strains were sensitive to gentamicin and 22% to norfloxacin; 90% of enterococci were sensitive to ampicillin, 41% to gentamicin and 7% to norfloxacin; all strains of Acinetobacter spp. were resistant to norfloxacin and 28% of strains were sensitive to gentamicin. Among strains recovered from wounds and ulcers; 33% of enterobacteria were sensitive to ampicillin, 45% to co-amoxiclav 53% to co-trimoxazole, 71% to ciprofloxacin and 75% to gentamicin. Sixty-six percent of P. aeruginosa strains were sensitive to gentamicin, 57% to ciprofloxacin and 91% to ceftazidime. All strains ofAcinetobacterspp. were sensitive to ampicillin sulbactam, 6% to ciprofloxacin and 23% to gentamicin; 29% strains of Staphylococcus aureus were resistant to methicillin (MRSA strains). Conclusions: Antibiotic-resistant and multiply resistant bacteria are frequently isolated from nursing home residents in the Ljubljana region. (Abstract truncated at 2000 characters).
Summary		Izhodišča: Med varovanci domov za ostarele so okužbe zelo pogoste. Pogosto jih povzročajo proti antibiotikom odporne bakterije, kar je velik problem za zdravljenje okužb. V prispevku avtorji prikazujejo pogostost bakterijskih rodov in vrst ter delež za antibiotike občutljivih sevov, osamljenih iz kužnin varovancev v domovih na območju Ijubljanske regije. Metode: V retrospektivni raziskavi so obravnavali bakterijske seve, ki so jih osamili iz kužnin ran, razjed in seča. Seve so v obdobju treh let (od januarja 2000 do decembra 2002) osamili pri rednem delu mikrobiološkega laboratorija Inštituta za varovanje zdravja. Analizirali so rezultate 196 sevov najpogosteje osamljenih rodov in vrst iz ran fer razjed ter 555 sevov najpogostejših rodov in vrst iz vzorcev seča. Rezultati: Pri bakterijskih sevih, ki so jih osamili iz vzorcev seča, je bila občutljivost za ampicilin pri enterobakterijah 12% in pri enterokokih 90%. Občutljivost za amoksicilin s klavulansko kislino in trimetoprim s sulfametoksazolom je bila pri enterobakterijah 35% in 32%; občutljivost za gentamicin pri enterobakterijah 73%, pri enterokokih 41%, pri povzročiteljih Pseudomonas aeruginosa 51 in pri acinetobaktru 28%; občutljivost za norfloksacin pri enterobakterijah 41%, pri enterokokih 7%, pri P. aeruginosa 22% in pri acinetobaktru 0%. Pri sevih iz ran in razjed je bila občutljivost za ampicilin pri enterobakterijah 33%, občutljivost za amoksicilin s klavulansko kislino in trimetoprim s sulfametoksazolom pa 45% in 53%. Občutljivost za gentamicin je bila pri enterobakterijah 75%, pri P. aeruginosa 66% in pri acinetobaktru 23%, občutljivost za ciprofloksacin pa pri enterobakterijah 71%, pri P. aeruginosa 57% in pri acinetobaktru 6%. Vsi sevi acinetobaktrov so bili občutljivi za ampicilin s sulbaktamom. Med sevi Staphylococcus aureus je bil delež proti meticilinu odpornih sevov (MRSA) 29%. (Izvleček skrajšan na 2000 znakov).
Descriptors		HOMES FOR THE AGED MICROBIAL SENSITIVITY TESTS ANTIBIOTICS DRUG RESISTANCE, MICROBIAL WOUND INFECTION AGED ENTEROBACTERIACEAE PSEUDOMONAS AERUGINOSA STAPHYLOCOCCUS AUREUS KLEBSIELLA