Author/Editor		Tekavčič-Pompe, M; Stirn-Kranjc, B; Brecelj, J
Title		Optic neuritis in children - clinical and electrophysiological follow-up
Type		članek
Source		Doc Ophthalmol
Vol. and No.		Letnik 107, št. 3
Publication year		2003
Volume		str. 261-70
Language		eng
Abstract		Optic neuritis (ON) in children usually ptesents with visual loss, relative afferent pupillary defect (RAPD), abnormal optic disc appearance, defects of visual field and colour vision, as well as with abnormalities of visual evoked potentials (VEP). Both, clinical and VEP parameters, improve after the attack; the time antil recovery, however, is as yet unknown.:The aim of this study was to follow-up children with ON for 1 yearand to determine clinical and VEP recovery. Twelve children (six with bilateral, six with unilateral ON) were studied in the acute phase and systematically followed-up for 1 year. The results show that initially, visual acuity was diminished in all eyes, while after 1 year, in only 14% of them. Optic disc appearance was abnormal in 83.3% of the eyes in the acute phase, and in 85% after 1 year. At the disease onset RAPD could be detected in 67%, visual field defects in 58.5%, and colour vision defects in 50% of eyes, but none of these abnormalities persisted in any eye until the end of study. VEP were abnormal in 83% of eyes in the acute phase and in 56% at the final follow-up.(at 6 or 12 monlhs). VEP normalization, when occurred, was mostly observed during the first 6 months. Complete clinical and VEP necovery was observed in three childrea. Both, clinical and electrophysiologicaI recovery in children with ON were relatively substantial and fast within the first year. VEP improvement may indicate better prognosis.
Descriptors		OPTIC NEURITIS EVOKED POTENTIALS, VISUAL COLOR VISION DEFECTS CHILD VISUAL ACUITY OPTIC DISK SCOTOMA FOLLOW-UP STUDIES