| Author/Editor | Jelenc, F | |
| Title | Dejavniki slabe prognoze bolnikov, radikalno operiranih zaradi raka želodca in ovrednotenje sistematične razširjene limfadenoktomije | |
| Type | monografija | |
| Place | Ljubljana | |
| Publisher | Medicinska fakulteta | |
| Publication year | 1992 | |
| Volume | str. 77 | |
| Language | slo | |
| Abstract | The study comprised 218 patients radically operated on for gastric cancer in the years 19831987, and 105 patients treated by surgery in the period from 1986 to 1990; in these, stomach resection was combined with systematically extended lymphadenectomy. The introduction presents recent knowledge on the epidemiology and etiology of gastric cancer. The importance of early diagnosis for a successful treatment of this disease is pointed out. Modern principles of gastric cancer surgery are presented and the technique of systematic extended lymphadenectomy described. The analysis of survival of 190 patients treated by radical surgery according to Kaplan-Meier's approach, and the evaluation of individual prognostic factors by means of Mantel-Cox test have shown that the depth of tumor invasion, regional lymph node involvement, cancer site in the stomach and the type of surgery are statistically significantly associated with worse survival of operated patients (p less th. 0.01). Sex and age turned out to be less relevant (p less th. 0.05). No statistically significant correlation could be estabiished between the histologic type of gastric cancer according to Lauren, Ming and WHO classification (p = 0.8159, p = 0.6468, p = 0.7682), and the survival of operated patients. Based on the analysis of the group of 105 patients in whom radical stomach resection was combined with systematic extended lymphadenectomy, no statistically significant differences in 5-year survival could be found between the group of 175 patients with RO resection (42.2 per cent ) and p = 0.6188, respectively). and the group of 93 radically operated patients with systematic extended lymphadenectomy (52 per cent ) (p = 0.082). A ditterence in survival, though insignificant, was established for stage pT1 (p = 0.0767) whereas there was no difference in survivai for stages pT2 and pT3 (p = 0.(trunc.) | |
| Descriptors | STOMACH NEOPLASMS LYMPH NODE EXCISION SURVIVAL RATE PROGNOSIS GASTRECTOMY NEOPLASM STAGING SEX FACTORS ADULT |