Author/Editor     Iglič, Aleš; Veranič, Peter; Jezernik, Kristijan; Fošnarič, Miha; Kamin, Boris; Haegerstrand, Henry; Kralj-Iglič, Veronika
Title     Spherocyte shape transformation and release of tubular nanovesicles in human erythrocytes
Type     članek
Source     Bioelectrochemistry
Vol. and No.     Letnik 62
Publication year     2004
Volume     str. 159-61
Language     eng
Abstract     We have studied dodecylmaltoside-induced echinocyte-spheroechincyte-spherocyte shape transformation and membrane vesiculation using transmission electron microscopy (TEM) on freeze-fracture replicas. It is indicated that spherical erythrocyte shape at higher dodecylmaltoside concentration is formed due to loss of membrane in the process where small, mostly tubular nanovesicles are released predominantly from the top of echinocyte and spheroechinocyte spicules.
Descriptors     ERYTHROCYTES
ERYTHROCYTE MEMBRANE
DETERGENTS
SPHEROCYTES
FREEZE FRACTURING
MICROSCOPY, ELECTRON