Author/Editor		Cotič, Dominik
Title		Utjecaj nekih čimbenika na rezultate endoskopskog liječenja vezikoureteralnog refluksa kolagenom
Type		monografija
Place		Zagreb
Publisher		Medicinski fakultet
Publication year		2001
Volume		str. 58
Language		cro
Abstract		Background. The purpose of this prospective study, which was done on Urologic clinic in Ljubljana, was to identify possible causes of unsuccessful treatment of vesicoureteric reflux (VUR) in children by endoscopic collagen injection under the ureteric oriffce. Patients and methods. Between February 1994 and september 1996, 130 primary VURs in 94 children aged 3 to 16 years were treated by endoscopic subureteric injection of collagen. Grade II reflux was found in 46 ureteric units, grade III in 55, and grade IV in 11 units. Seventy-seven children had normal micturiction and 17 showed signs of unstable bladder. The collagen injection was performed under general anasthesia. All children had a follow-up assessment on average 5.1 months after the first injection of collagen. They were evaluated by micturiction cystography and ultrasound examination of the urinary tract. Results. A single injection of collagen eliminated VUR in 74 (56.9 %) cases. There was a statistically significant correlation between the grade of VUR and the success rate of collagen therapy (p < 0.01).The average amount of collagen used in cured and in non cured children was 0.55 ml and 0.76 ml, respective(y (p < 0.01). Children with normal appearance of the ureteric oriffice had significantly better results compared to other children (p < 0.01). There was no statistically significant correlation between the success rate of treatment and the place of the colagen injection or the shape of the uretric orifice following the injection. A statistically significant correlation, however, was found between the function of the lower urinary tract and the results of endoscopic collagen treatment for VUR (p < 0.05). Ultrasound showed no obstruction of the upper urinary tract after the aplication of the collagen injection. (Abstract truncated at 2000 characters)
Descriptors		VESICO-URETERAL REFLUX CYSTOSCOPY COLLAGEN CHILD AGE FACTORS SEX FACTORS TREATMENT OUTCOME