Author/Editor		Bizjak, Bojana; Urlep-Šalinović, Vera
Title		Povečanje varnosti transfuzije krvi novorojenčkov z večkratno uporabo filtriranih krvnih komponent enega dajalca
Translated title		Increased safety of blood transfusion for infants and neonates with repeated use of leukocyte - reduced blood of one donor
Type		članek
Source		Zdrav Vestn
Vol. and No.		Letnik 73, št. Suppl 1
Publication year		2004
Volume		str. I-85-7
Language		slo
Abstract		Background. As neonates are among the most frequent recipients of blood components, they are exposed to large numbers of blood donors. This, and particularly their immune immaturity, puts them at high risk of posttransfusion complications. When preparing blood components for neonates, we try to make the components as safe as possible, decreasing the neonate's exposition to a large number of blood donors. We wanted to know whether our attempts to reach this aim by applying filtration for all blood components, concentrated erythrocytes, fresh frozen plasma and thrombocyte concentrate was successful. The blood components were divided into small doses using the method of sterile connection and assuring the components of a single donor. Methods. Whole blood was filtered within 6 hours after withdrawal in the closed blood-bag system - in line filtration. Filtered concentrated erythrocytes and filtered fresh frozen plasma are thus obtained. Thrombocyte plasma is filtered on order Using sterile connection, the bags for further division of blood components are then connected to the bags with the individual blood components. Results. In the past year, 62 neonates received two or more blood components. They received a total of 383 transfusions, an average of 6.17 blood components per infant. Altogether, the neonates received the blood components of 224 blood donors and were exposed to 3.45 donors on the average. The range of the number of donors, whose blood components were received by the infants, was between one and up to 24 donors, to which two infants were exposed. Conclusions. At our department we follow the recommendations of the European Council. All blood components for neonates are filtered, and from one donor if possible. We were extremely successful in decreasing the exposition of the neonates to large numbers of blood donors. (Abstract truncated at 2000 characters).
Summary		Izhodišča. Novorojenčki so med najpogostejšimi prejemniki krvnih komponent. S tem jih izpostavljamo velikemu številu različnih krvodajalcev. Zaradi tega in svoje, zlasti imunske, nezrelosti so močno ogroženi za nastanek posttransfuzijskih zapletov, zato zanje skušamo pripraviti čim varnejše krvne komponente in zmanjšati izpostavljenost večjemu številu krvodajalcev. Zanimalo nas je, ali smo bili pri tem uspešni z uporabo filtriranih vseh krvnih komponent, koncentriranih eritrocitov, sveže zmrznjene plazme in trombocitnega koncentrata. Krvne komponente smo delili v majhne odmerke z metodo sterilnega varjenja in zagotavljali komponente enega dajalca. Metode. Filtrirali smo polno kri šest ur po odvzemu v zaprtem sistemu odvzemnih vrečk - in line filtracija. Tako smo pridobili filtrirane koncentrirane eritrocite in filtrirano sveže zmrznjeno plazmo. Trombocitno plazmo smo filtrirali po naročilu. Nato smo vrečkam s posamezno krvno komponento sterilno privarili vrečke za nadaljnje deljenje krvne komponente. Rezultati. 62 novorojenčkov je lani prejelo dve ali več krvnih komponent. Skupaj so prejeli 383 transfuzij, povprečno 6,17 krvne komponente po otroku, s tem pa krvne komponente 214 krvodajalcev in bili povprečno izpostavljeni 3,45 krvodajalcem. Razpon števila krvodajalcev, katerih krvne komponente so prejeli otroci, je bil od enega do celo 24 krvodajalcev, katerim sta bila izpostavljena dva otroka. Zaključki. Na našem oddelku sledimo priporočilom Sveta Evrope in pripravljamo za novorojence vse krvne komponente filtrirane, po možnosti od enega dajalca. Uspelo nam je zmanjšati izpostavljenost novorojenčkov velikemu številu krvodajalcev. Namesto 383 krvodajalcev so otroci prejeli krvne komponente samo 214 krvodajalcev. Tako smo zmanjšali izpostavljenost za 55,9%.
Descriptors		BLOOD COMPONENT TRANSFUSION BLOOD COMPONENT REMOVAL BLOOD DONORS SAFETY INFANT, NEWBORN