Author/Editor		Kramar, Irena; Kariž, Stojan; Plazar, Nadja
Title		Ugotavljanje vzrokov hemolize po transfuziji krvi pri bolnici z ulceroznim kolitisom
Translated title		Finding the right cause for hemolysis in patient with ulcerative colitis after blood transfusion
Type		članek
Source		Zdrav Vestn
Vol. and No.		Letnik 73, št. Suppl 1
Publication year		2004
Volume		str. I-135-7
Language		slo
Abstract		Background. Acute hemolysis is a tempestuous life threatening disease. Finding the right couse as soon as possible is very important for the beginning of the right therapy. Because of its quick development there is a frequent lack of time to find exact causes and to prevent its development. Methods and materials. A case of 62 year old female patient with ulcerative colitis, sideropenic anemia and febrile neutropenia is presented. She received a transfusion of 2 units of packed red blood cells. The following day she developed massive acute intravascular hemolysis with shock and multiple organ failure. She died within 24 hours after receiving the transfusion. Results. If the outset of hemolysis begins after blood transfusion, we have to exclude unwanted side effects of such terapy as the reason for hemolysis.
Summary		Izhodišča. Akutna hemoliza je burno dogajanje, ki je lahko usodno za bolnika. Pravočasno in pravilno spoznanje vzroka za pospešeno razgradnjo eritrocitov je pomembno za pravilno zdravljenje. Pri hitrem razvijanju klinične slike akutne hemolize pa pogosto ni dovolj časa ali možnosti, da najdemo prave vzroke za njen nastanek in preprečimo njen razvoj. Bolniki in metode. Opisan je primer 62-letne bolnice z ulceroznim kolitisom, sideropenično anemijo in febrilno nevtropenijo. Prejela je transfuzijo 2 enot koncentriranih eritrocitov, po kateri je prišlo do nastanka masivne akutne znotrajžilne hemolize z razvojem šokovnega stanja in odpovedi več organov. Bolnica je umrla v okviru 24 ur po prejemu transfuzije. Zaključki. Kadar je bolnik pred pojavom znakov akutne hemolize prejel transfuzijo krvi ali njenih sestavin, moramo upoštevati možnost neželenega učinka transfuzije.
Descriptors		COLITIS, ULCERATIVE ANEMIA, IRON-DEFICIENCY NEUTROPENIA ERYTHROCYTE TRANSFUSION HEMOLYSIS MIDDLE AGE MULTIPLE ORGAN FAILURE