Author/Editor     Novaković, Srdjan
Title     Current status in the field of tumor vaccines
Type     članek
Source     In: Kramar P, Miklavčič D, editors. Proceedings of the International scientific workshop and postgraduate course Electroporation based technologies and treatments; 2003 Nov 19-22; Ljubljana. Ljubljana: Faculty of electrical engineering,
Publication year     2003
Volume     str. 51-3
Language     eng
Abstract     Among the most attractive and promising variants of cancer immunotherapy, a special place is reserved for tumor vaccines. Until now, many outstanding approaches for the creation of tumor vaccines have been developed that exploit the latest knowledge in immunology, tumor physiology, as well as in molecular biology. With regard to the basic principles of the vaccine creation and their expected activity, the tumor vaccines could be divided into two subclasses: I) firstgeneration vaccines that base on the principles of classical immunology - i.e. classical tumor vaccines, and II) second-generation vaccines that base on the principles of molecular immunology genetically modified and recombinant tumor vaccines. With no intention to be comprehensive, I will try to review some of the approaches for the creation of tumor vaccines as well as to discuss their future perspectives.
Descriptors     NEOPLASMS
CANCER VACCINES