Author/Editor		Žvan, Bojana; Zaletel, Marjan
Title		Možganskožilne bolezni pri ženskah
Type		članek
Source		Slov Kardiol
Vol. and No.		Letnik 1, št. 1
Publication year		2004
Volume		str. 30-3
Language		slo
Abstract		Interest in and knowledge about the importance of stroke in women are increasing because of the demonstration of a higher mortality, higher disability and higher incidence of dementia in women who survive a stroke. Stroke prevention is essentially based on the identification and treatment of risk factors. Knowledge of sex differences might be of interest in improving preventive strategies and the in-hospital management of stroke patients. We analyzed data of 232 stroke patients admitted in our hospital from July to December 2003. In all patients we performed ultrasound investigation of neck arteries, ECG and cholesterol level. In addition we fulfilled questionnaire about risk factors. We found significantly higher rates of alcohol abuse (p=0.048) and cigarette smoking (p=0.016) in men. Atrial fibritlation was found to be significantly higher in women when compared to men (p=0.013). However, rates of lipid plaques (p=0.038) as well as stenosis of internal carotid artery over 70% (p=0.07) were higher in men than in women. It seems that atrial fibrillation is more important cause of stroke in women, while atherothrombosis in men.
Summary		Zanimanje za možganskožilne bolezni pri ženskah se povečuje zaradi velike umrljivosti. Preprečevanje možganske kapi temelji na prepoznavanju dejavnikov tveganja za možganskožilne bolezni in ukrepanju zoper nje. Poznavanje razlik v dejavnikih tveganja med spoloma bi lahko pripomoglo k boljšemu preprečevanju možganske kapi pri obeh spolih. Na Kliničnem oddelku za nevrologijo Kliničnega centra v Ljubljani smo analizirali 232 bolnikov, ki so bili pregledani v nevrosonološki ambulanti od julija do decembra meseca 2003. Vsem preiskovancem smo pregledali vratne arterije z duplex ultrazvočno preiskavo, posneli smo EKG, določili vrednost serumskega holesterola in izpolnili vprašalnik o dejavnikih tveganja. Ugotovili smo, da pomembno več moških prekomerno uživa alkoholne pijače (p = 0,048) in kadi (p = 0,016). Delež žensk, ki imajo atrijsko fibrilacijo (p = 0,013), je pomembno večji od deleža moških. Manjši je delež žensk, ki imajo maščobne lehe (p=0,038) in zožitev notranje karotidne arterije nad 70% (p = 0,07). Izgleda, da je atrijska fibrilacija pomembnejši vzrok za ishemično možgansko kap pri ženskah, medtem ko je aterotromboza pomembnejši vzrok za možgansko ishemijo pri moških.
Descriptors		CEREBROVASCULAR DISORDERS CEREBRAL INFARCTION CEREBRAL ISCHEMIA, TRANSIENT CAROTID ARTERIES RISK FACTORS SEX FACTORS TOMOGRAPHY, X-RAY COMPUTED CAROTID STENOSIS HYPERTENSION DIABETES MELLITUS ALCOHOL DRINKING SMOKING HYPERCHOLESTEROLEMIA