Author/Editor		Batta, Mirela; Turčin, Arijana; Kores-Plesničar, Blanka
Title		Psihiatrični vidiki Huntingtonove bolezni - prikaz primerov
Translated title		Psychiatric aspects of Huntington disease - case reports
Type		članek
Source		Zdrav Vestn
Vol. and No.		Letnik 73, št. 4
Publication year		2004
Volume		str. 239-42
Language		slo
Abstract		Background. Huntington disease occurrs rarely, it can be encountered not only by neurologists and psychiatrists but also by other medical practitioners. Its characteristic features are involuntary movements, cognitive disorders and gradual development of dementia. Diagnosis is given on the basis of these clinical features, positive familial anamnesis, with the laboratory exclusion of other neuropsychiatric diseases and with the help of neuroimaging methods (in particular NMR). The disease can be only confirmed by means of genetic analysis. Patients and methods. In this article, four cases of patients with Huntington disease and diverse psychiatric disorders that were hospitalised at the psychiatric department of the Maribor General Hospital between October 2002 and March 2003 are described. All the patients fulfilled the valid criteria for the diagnosis of Huntington disease. However, they differed according to their accompanying psychiatric psychopathology, age and social problems. Conclusions. The purpose of this article is to draw attention to different psychiatric symptoms and clinical manifestations of Huntington disease that are often misleading in the diagnostic process. In addition, exigency of early diagnostics, guidelines for referrals to genetic testing and psychiatric monitoring of these patients care emphasised.
Summary		Izhodišča. Huntingtonova bolezen se redko pojavlja, a se s temi bolniki lahko srečajo poleg nevrologov in psihiatrov tudi ostale stroke. Značilni zanjo so nehoteni zgibki, kognitivne motnje in postopen razvoj demence. Diagnoza se postavi na temelju klinične slike, pozitivne družinske anamneze, z laboratorijsko izključitvijo nekaterih drugih nevropsihiatričnih bolezni ter z nevroradiološkimi metodami (s poudarkom na magnetnoresonančnem slikanju - MB), potrdi pa se lahko le z genetsko analizo. Bolniki in metode. V prispevku so opisani štirje primeri bolnikov s Huntingtonovo boleznijo in različnimi psihiatričnimi motnjami, ki so bili zdravljeni na psihiatričnem oddelku Splošne bolnišnice Maribor v obdobju od oktobra 2002 do marca 2003. Vsi opisani bolniki so izpolnjevali veljavna merila za diagnozo Huntingtonove bolezni, razlikovali pa so se po pridruženi psihopatologiji, starosti in spremljajoči socialni problematiki. Zaključki. Prispevek opozarja na različne psihiatrične simptome in klinične slike Huntingtonove bolezni, ki pogosto lahko zameglijo diagnosticiranje. Zato je potrebna zgodnja diagnostika, oblikovanje smernic pri odločanju za napotitev na genetske preiskave in nujnem psihiatričnem spremljanju teh bolnikov.
Descriptors		HUNTINGTON'S DISEASE MENTAL DISORDERS DEMENTIA PERSONALITY DISORDERS DEPRESSION ANXIETY DISORDERS