Author/Editor | Toth, T | |
Title | Intestinal lesions produced experimentally by heat exposure | |
Type | članek | |
Source | Exp Clin Gastroenterol | |
Vol. and No. | Letnik 1, št. 1 | |
Publication year | 1991 | |
Volume | str. 83-6 | |
Language | eng | |
Abstract | Lesions of the mucosa of the small intestine were produced experimentally by exposure of the rats to high environmental temperature. The first change was subnuclear vacuolization of the absorptive epithelial cells on the top of the villi intestinales. By the coalescence on these vacuoles subnuclear clefts were formed and the shedding of the elevated cells, as well as the autolysis of the denuded villi, occurred. The presence of an eosinophilic material in the clefts in some cases and the higher cellularity of the stroma are evidence of the non-artificial nature of these changes. These experiments can serve as a simple model to simulate human ischemic (necrotic) enteritis | |
Descriptors | INTESTINE, SMALL HEAT INTESTINAL MUCOSA RATS, INBRED STRAINS RATS |