Author/Editor     Toth, T
Title     Intestinal lesions produced experimentally by heat exposure
Type     članek
Source     Exp Clin Gastroenterol
Vol. and No.     Letnik 1, št. 1
Publication year     1991
Volume     str. 83-6
Language     eng
Abstract     Lesions of the mucosa of the small intestine were produced experimentally by exposure of the rats to high environmental temperature. The first change was subnuclear vacuolization of the absorptive epithelial cells on the top of the villi intestinales. By the coalescence on these vacuoles subnuclear clefts were formed and the shedding of the elevated cells, as well as the autolysis of the denuded villi, occurred. The presence of an eosinophilic material in the clefts in some cases and the higher cellularity of the stroma are evidence of the non-artificial nature of these changes. These experiments can serve as a simple model to simulate human ischemic (necrotic) enteritis
Descriptors     INTESTINE, SMALL
HEAT
INTESTINAL MUCOSA
RATS, INBRED STRAINS
RATS