Author/Editor		Skačej, Helena; Friedrich, Tomaž
Title		Elektrofiziološka ocena delovanja čepnic pri bolnikih s pigmentno retinopatijo
Type		monografija
Place		Ljubljana
Publisher		Medicinska fakulteta
Publication year		2003
Volume		str. 66
Language		slo
Abstract		BACKGROUND. Full-field electroretinography (ERG) is the fundamental electrophysiological examination test which evaluates the retina function. It is performed in compliance with the standard recording procedure. The latter is readily modified according to new research results in order to improve the clinical value of the investigation. Full-field ERG is important in dealing with patients having the most common retina dystrophy the retinitis pigmentosa (RP). This disease is clinically and genetically a very diverse condition with characteristically progressive and generalized degeneration of rods, cones and consequently also other cells of the retina. Besides full-field ERG which is an objective examination, also various psychophysical investigations are used to recognize and monitor RP. The most important among them are the measurements of the visua) acuity and thc visual field. AIM. The normative values for the full-field ERG with a new stimulator producing higher luminance stimuli (Ilashes) than the present stimulator had to be determined by this research. We wanted to check the effect of the high luminance to the patients with RP. To stimulate cones which are still preserved in the course of the disease we also introduced averaging the responses with higher number of stimuli, this being a novelty to the standard recording procedures. This was supposed to evaluate the cone function with RP patients more objectively. With these patients we also wanted to determine to what degree the full-field ERG responses are correlated with the visual acuity and the visual field. HYPOTHESIS. 1. Due to higher luminance stimuli higher full-field ERG responses were expected with RP patients as well as with the control group. 2. For RP patients more recordable cone responses were awaited due to averaging the responses with higher number of stimuli. 3. Full-filed ERG responses, visual acuity and visual field were anticipated to be correlated. (Abstract truncated at 2000 characters).
Descriptors		RETINITIS PIGMENTOSA ELECTRORETINOGRAPHY SCOTOMA PHOTIC STIMULATION CONES (RETINA) VISUAL ACUITY PERIMETRY VISUAL FIELDS