Author/Editor		Čizmarevič, Bogdan; Didanovič, Vojko; Lanišnik, Boštjan
Title		Primarno kirurško zdravljenje napredovalih malignih tumorjev nosne votline in obnosnih votlin
Translated title		Primary surgical treatment of advanced malignant tumours of the nose and paranasal sinuses
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 43, št. Suppl 3
Publication year		2004
Volume		str. 139-43
Language		slo
Abstract		Malignant tumours of the nasal and paranasal cavities are rare. Most of them are already in an advanced stage at the time of diagnosis. However, many patients are cured with combined radical surgical therapy and radiotherapy. Because of the rarity of these tumours and their histological diversity, it is difficult to find statistically significant factors. This article presents the results and histologic pattern for patients managed at our department during the past six years. As expected, the majority of these patients had squamous cell carcinoma. Although the number of patients with squamous cell carcinoma is small, it can be concluded that the most important factor of survival is the possibility of radical tumour removal and postoperative irradiation. In spite of the fact that most patients had locally advanced tumours, at the beginning of management none of them had regional metastases. The overall five-year survival of these patients is 64%.
Summary		Maligni tumorji nosne votline in obnosnih votlin so redki. Večinoma so odkriti v zelo napredovalem stadiju. Radikalno kirurško zdravljenje s pooperacijskim obsevanjem daje velike možnosti za ozdravitev. Zaradi majhnega števila tumorjev in zelo raznolike histološke sestave malignomov ni možno potrditi statistično pomembnih pokazateljev. V članku je prikazan rezultat zdravljenja in histološka slika bolnikov, ki so bili zdravljeni v šestletnem obdobju na oddelku za ORL (otolaringologijo) in CFK (cervikofacialno kirurgijo) SB (Splošne bolnišnice) Maribor. Kot povsod imamo tudi pri nas največ bolnikov s ploščatoceličnimi karcinomi in majhno število bolnikov z zelo različnimi histološkimi diagnozami. Čeprav je tudi število bolnikov s ploščatoceličnim karcinomom majhno, lahko ugotovimo, da je za preživetje najpomembnejša možnost radikalne odstranitve karcinoma, ki ji sledi pooperacijsko obsevanje. Velika večina bolnikov prihaja na zdravljenje z lokalno zelo napredovalimi tumorji, kljub temu pa nismo v začetku zdravljenja odkrili regionalnih zasevkov. Petletno preživetje naših bolnikov s ploščatoceličnimi karcinomi je 64%.
Descriptors		NOSE NEOPLASMS PARANASAL SINUS NEOPLASMS NEOPLASM STAGING CARCINOMA, SQUAMOUS CELL ADENOCARCINOMA CARCINOMA, ADENOID CYSTIC SURVIVAL ANALYSIS