Author/Editor		Aničin, Aleksandar; Žargi, Miha
Title		Zdravljenje zasevkov na vratu pri bolnikih s karcinomom grla - značilnosti področne ponovitve
Translated title		Management of metastases cervical lymph nodes in patients with laryngeal carcinoma - patterns of failure
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 43, št. Suppl 3
Publication year		2004
Volume		str. 269-72
Language		slo
Abstract		The purpose of the study was to present the patterns of regional failure when neck dissection is chosen as part of laryngeal cancer surgery. From January 1, 1987 through December 31, 1991, 374 neck dissections were performed in 207 patients with laryngeal squamous cell carcinoma, of which 87% were selective neck dissections. The overall regional recurrence rate was 4.84% and the average duration of follow-up 58 months after surgery. The regional in-field recurrence rates after selective neck dissection in postoperatively irradiated N2b and N1 patients were 12.5% and 8.3%, respectively. It seems that a more extensive neck dissection would not benefit these patients, because the majority of regional recurrences developed in the dissected field. Selective neck dissection with postoperative radiotherapy thus represents an appropriate therapeutic and not only diagnostic procedure in the treatment of patients with laryngeal carcinoma, even for N2b cases.
Summary		Namen študije je bil raziskati značilnosti področne ponovitve bolezni pri bolnikih s karcinomom grla, ki so bili zdravljeni kirurško, vključno z disekcijo bezgavk na vratu. Od 1. januarja 1987 do 31. decembra 1991 smo pri 207 bolnikih s ploščatoceličnim karcinomom grla opravili 374 disekcij na vratu (87% selektivnih disekcij). Bolnike smo opazovali povprečno 58 mesecev po posegu in zabeležili področno ponovitev bolezni v 4,84%. Incidenca področne ponovitve bolezni v polju disekcije, pri bolnikih, ki so bili po selektivni disekciji na vratu zdravljeni z obsevanjem, je bila 12,5% v stadiju N2b oziroma 8,3% v stadiju N1. Obsežnejša izpraznitev vratu pri teh bolnikih najverjetneje ne bi bila smiselna, saj je večina področnih ponovitev nastala v polju disekcije. Zdravljenje zasevkov na vratu pri bolnikih s karcinomom grla s selektivno disekcijo in obsevanjem po posegu je primeren terapevtski in ne le diagnostični postopek, ki je umesten tudi v stadiju N2b.
Descriptors		LARYNGEAL NEOPLASMS CARCINOMA, SQUAMOUS CELL LYMPHATIC METASTASIS LYMPH NODE EXCISION NEOPLASM STAGING LARYNGECTOMY RADICAL NECK DISSECTION NEOPLASM RECURRENCE, LOCAL