Author/Editor     Grdinić, V; Jakševac-Mikša, M; Briški, D
Title     Kompjutorska podrška u kontroli kakvoće lijekova. 4. HPLC postupak
Translated title     Computer-aided pharmaceutical quality control. 4. HPLC procedure
Type     članek
Source     Farm Glas
Vol. and No.     Letnik 47, št. 10
Publication year     1991
Volume     str. 279-85
Language     cro
Abstract     The way of standardization the HPLC procedure for determination of the salicylic acid, as an impurity in preparations containing aspirin, is presented. For this purpose the computer expert system ESKULAP was applied to a set of 24 data blocks classified in 6 groups with 4 values each. Calculations involving standard statistical tests are described for estimating the reliability of analytical results. The method of least squares was used as the basis of standard evaluation. The evaluation of experimental results, particularly through data homogenity, showed that tested analytical procedure can be proclaimed as standard
Descriptors     CHROMATOGRAPHY, HIGH PRESSURE LIQUID
DRUGS
QUALITY CONTROL
SOFTWARE
SALICYLIC ACIDS