Author/Editor		Bratanič, Borut; Novosel-Sever, Marjeta; Paro-Panjan, Darja
Title		Bakterijske okužbe v poznem obrojstnem obdobju
Translated title		Late neonatal bacterial infections
Type		članek
Source		In: Novak-Antolič Ž, editor. Bakterijske okužbe v perinatologiji. 12. Novakovi dnevi z mednarodno udeležbo; 2004 maj 14-15; Laško. Ljubljana: Slovensko zdravniško društvo, Združenje za perinatalno medicino,
Publication year		2004
Volume		str. 74-81
Language		slo
Abstract		Background. Bacterial infections of new-borns are despite a relatively big array of antibiotics still very serious diseases. The purpose of this article was to analyse late neonatal bacterial sepsis according to causative agents, characteristics of patients and diagnostic procedures on Special care Neonatal Unit (NO) at Paediatric Department University Medical Centre of Ljubljana. Methods. Discharge summaries of all newborn patients with the diagnoses of sepsis and suspected sepsis from the three years (2001-2003) were retrospectively analysed according to the special protocol. All hospital (nosocomial) infections in new-borns are routinely followed up. Results. Among 1367 discharged new-born infants there were 97 who had aforementioned diagnoses and in 7 (7.2%,) positive blood culture confirmed late neonatal bacterial sepsis. Two times Escherichia coli and Staphylococcus epidermidis and one time Enterococcus faecalis, Streptococcus pyogenes and coagulase negative Stphyllococcus were isolated. New-borns with confirmed late neonatal sepsis had elevated concentrations of C-reactive protein (CRP) in blood and altered proportions between young and mature granulocytes and total number of leukocytes. As an additional diagnostic maker for neonatal sepsis the procalcitonin (PCT) concentration in newborns' blood has been determined. Nobody of our septic patients died or suffered serious consequences of late neonatal sepsis. During last three years less than 1% patients at NO had hospital infections, taking into account also viruses as causing agents (an incidence density of 1,2 per 1000 patient days). Conclusions. Late neonatal sepsis appears to be relatively benign disease at NO taking in account the characteristics of the admitted new-born population and the procedures during hospitalisation. Besides appropriate antibiotic treatment, prophylactic measures for constant prevention of spreading nosocomial infections are of equal importance.
Descriptors		INFANT, NEWBORN, DISEASES BACTERIAL INFECTIONS SEPSIS CROSS INFECTION INFANT, NEWBORN