Author/Editor		Zupan, Igor
Title		Akutni koronarni sindrom in maligne aritmije - farmakološko ali nefarmakološko zdravljenje
Translated title		Acute coronary syndrome and malignant arrhythmias - pharmacologic or non-pharmacologic treatment
Type		članek
Source		In: Bručan A, Gričar M, Vajd R, editors. Urgentna medicina: izbrana poglavja. Zbornik 11. mednarodni simpozij o urgentni medicini; 2004 jun 9-12; Portorož. Ljubljana: Slovensko združenje za urgentno medicino,
Publication year		2004
Volume		str. 55-60
Language		slo
Abstract		Sustained ventricular tachycardia and fibrillation occur in up to 20% of patients with acute myocardial infarction and have been associated with a poor prognosis. The prognosis of ventricular arrhythmias among patients with non-ST elevation acute coronary syndrome is unknown. Sudden death from cardiac causes is estimated to account for approximately 50 percent of all deathsfrom cardiovascular causes. Clinical trials have shown that antiarrhythmic-drug therapy is not effective in reducing mortality among patients who are assumed to be at risk for such death, but recent randomized trials have demonstrated a survival benefit in high-risk patients of therapy with an implantable cardioverter-defibrillator, as compared with conventional drug therapy. A challenge for the future is the development of new approaches or techniques that will allow screening for markers of increased risk of fatal ventricular arrhythmias in large general populations, in which the relative risk is low but the number of deaths due to arrhythmia is high.
Descriptors		ANGINA, UNSTABLE MYOCARDIAL INFARCTION VENTRICULAR FIBRILLATION TACHYCARDIA, VENTRICULAR DEATH, SUDDEN, CARDIAC SURVIVAL ANALYSIS ANTI-ARRHYTHMIA AGENTS DEFIBRILLATORS, IMPLANTABLE