Author/Editor | Gokce, Isa; Anderluh, Gregor; Lakey, Jeremy, Hugh | |
Title | Fusion proteins | |
Type | monografija | |
Place | New Castle | |
Publisher | World intellectual property organization | |
Publication year | 2003 | |
Language | eng | |
Abstract | The present invention relates to fusion proteins (fusion polypeptides), particularly for use in expression and/or purification systems. The present inventors have found that the To IAIII domain has remarkable properties which are of particular use as a fusion protein partner to achieve high levels of expression in a host cell. In one aspect of the invention, a ToIAIII domain or a functional homologue, fragment, or derivative thereof is located towards the N-tetminus of the fusion polypeptide and a non-ToIA polypeptide is located towards the C-terminus of the fusion polypeptide. | |
Descriptors | RECOMBINANT FUSION PROTEINS PATENTS |