Author/Editor     Gokce, Isa; Anderluh, Gregor; Lakey, Jeremy, Hugh
Title     Fusion proteins
Type     monografija
Place     New Castle
Publisher     World intellectual property organization
Publication year     2003
Language     eng
Abstract     The present invention relates to fusion proteins (fusion polypeptides), particularly for use in expression and/or purification systems. The present inventors have found that the To IAIII domain has remarkable properties which are of particular use as a fusion protein partner to achieve high levels of expression in a host cell. In one aspect of the invention, a ToIAIII domain or a functional homologue, fragment, or derivative thereof is located towards the N-tetminus of the fusion polypeptide and a non-ToIA polypeptide is located towards the C-terminus of the fusion polypeptide.
Descriptors     RECOMBINANT FUSION PROTEINS
PATENTS