Author/Editor		Brvar, Miran; Možina, Hugon; Osredkar, Joško; Možina, Martin; Noč, Marko; Bručan, Andrej; Bunc, Matjaž
Title		S100B protein in carbon monoxide poisoning: a pilot study
Type		članek
Source		Resuscitation
Vol. and No.		Letnik 61
Publication year		2004
Volume		str. 357-60
Language		eng
Abstract		Carbon monoxidc (CO) poisoning is the most common form of Iethal poisoning. The aim of this prospective clinical study was to assess the possible role of S100B, the structural protein in the astroglia, as a biochemical marker of brain injury in carbon monoxide poisoning. Serum S100B determination was performed in 38 consecutive patients poisoned by carbon monoxide who were admitted to the Emergency Department (ED) in Ljubljana. All three unconscious patients had elevated S100B Ievels. The patient with the highest S100B died. S100B was elevated in two of the six patients with initial transitory unconsciousness at the scene. All 29 patients without loss of consciousness had normal S100B Ievels. Carbon monoxide poisoning appears to be associated with elevated S100B levels.
Descriptors		CARBON MONOXIDE POISONING ASTROCYTES INTENSIVE CARE UNITS NERVE TISSUE PROTEIN S 100 UNCONSCIOUSNESS HYPERBARIC OXYGENATION PROGNOSIS