Author/Editor     Miljković, Jovan; Marko, Pij Bogomir
Title     Grover's disease: successful treatment with acitretin and calcipotriol
Type     članek
Source     Wien Klin Wochenschr
Vol. and No.     Letnik 117, št. Suppl 2
Publication year     2004
Volume     str. 81-3
Language     eng
Abstract     A 74-year-old man presented with a fivemonth history of highly pruritic keratotic papules on the trunk and extremities. Laboratory data revealed mild eosinophilia, elevated IgE (483 KE/I) and no other signs of atopy. Tests to exclude parasitic infestation were negative. Two biopsies showed non-specific changes. The third biopsy revealed small acantholytic clefts in the upper part of the epidermis and confirmed the diagnosis of Grover's disease. Topical treatment with calcipotriol ointment and systemic treatment with acitretin in low doses successfully reduced the pruritus within one week, and brought about a complete remission within three weeks without any recurrence.
Descriptors     ACANTHOLYSIS
ACITRETIN
CALCITRIOL
AGED