Author/Editor		Grad, A; Kiauta, T; Osredkar, J
Title		Plasma norepinephrine and electrocardiographic changes in ischemic stroke and subarachnoid hemorrhage
Type		članek
Source		Zdrav Vestn
Vol. and No.		Letnik 61, št. 7
Publication year		1992
Volume		str. 331-3
Language		eng
Abstract		Background. Ischemic cerebrovascular stroke and particularly subarachnoid hemorrhage may be associated with cardiac abnormalities, including arrhythmias and other electrocardiographic changes of obscure mechanism. In our study we compared the frequency of electrocardiographic abnormalities after cerebrovascular incident in patients with high and in those with normal plasma norepinephrine levels. Methods. We evaluated electrocardiographic abnormalities and plasma norepinephrine concentrations in 79 patients (39 patienrs with ischemic stroke and 40 patients with subarachnoidal hemorrhage) within the first 24 hours, at 72 hours and seven days after the onset of ischemic stroke or subarachnoid hemorrhage. Results. In the 36 patients who had elevated plasma norepinephrine concentrations within the first 24 hours after the incident, sinus tachycardia (p less th. 0.01) and negative T waves (p less th. 0.01) were more freguent than in the 43 patients with normal plasma norepinephrine concentrations. After 72 hours sinus tachycardia (p less th. 0.01) and T wave abnormaliries were found with increased freguency in the 40 patients with increased plasma norepinephrine concentrations. One week after the incident, only sinus tachycardia was found with increased freguency (p less th. 0.01) in the 34 patients with high plasma norepinephrine concentrations. QT prolongation, U waves, ST depression and arrhythmias were found with similar freguency in patients with elevated and in those with normal plasma norepinephrine concentrations. plasma norepinephrine concentrations. Conclusions. With the exception of sinus tachycardia and negative T waves, electrocardiographic changes in patients with subarachnoid hemorrhage do not seem to directly depend on elevated.
Descriptors		CEREBROVASCULAR DISORDERS ELECTROCARDIOGRAPHY NOREPINEPHRINE CEREBRAL ISCHEMIA HEART RATE ARRHYTHMIA SUBARACHNOID HEMORRHAGE