Author/Editor     Pospisil, L; Stroblova, H; Canderle, J; Unzeitig, V
Title     The chlamydial heat shock protein (cHSP60) in females participating in fertilization programs (a serological study)
Type     članek
Source     Acta Dermatovenerol Alp Pannon Adriat
Vol. and No.     Letnik 13, št. 3
Publication year     2004
Volume     str. 75-8
Language     eng
Abstract     Background: Hit shock protein a possible parameter for assessement of chlamidial infections. Materials: The incidence of IgG antibodies against the chlamydial heat shock protein (cHSP60) and against the species-specific chlamydial major outer membrane protein (MOMP) of Chlamydia trachomatis (C. t.J and Chlamydia pneumoniae (C. p.) in the blood serum of 70 females attending a fertilization program due to fertility disorders were estimated, and the results compared with those obtained from 50 females suffering from pelvic inflammatory disease (PID) and from 51 female blood donors respectively. Results: The anti-cHSP60 antibodies have been ascertained as follows: in 26 women from the first group (37.1 %), in 16 of the second group (32.0 %) and in 12 (23.5 %) of the last group. The occurrence of the anti- cHSP60 antibodies in the groups examined was statistically insignificant. Similarly no difference in the occurrence of the species-specific anti-MOMP antibodies C. t. and C. p. were found in the groups examined. Conclusion: The occurrence of species-specific antibodies against C. t. in women of all groups with positive reaction anti cHSP60 is significantly higher than in those without the antibodies against cHSP60, but against C, p. the phenomenon was observed only in the group of the blood donors.
Descriptors     ADNEXITIS
CHLAMYDIA INFECTIONS
CHLAMYDIA TRACHOMATIS
CHLAMYDIA PNEUMONIAE
CHAPERONIN 60
BACTERIAL OUTER MEMBRANE PROTEINS
IGG
ANTIBODIES, BACTERIAL
FERTILIZATION IN VITRO