Author/Editor		Ihan, Alojz; Rojc, Bojan
Title		Imunski sistem in sindrom odvisnosti od alkohola
Type		članek
Source		In: Boben-Bardutzky D, Užmah-Kučina A, editors. Medicina odvisnosti, medicina sodelovanja. Zbornik 6. konference o medicini odvisnosti; 2004 okt; Vojnik. Ljubljana: Sanofi-Synthelabo, Lek,
Publication year		2004
Volume		str. 23-8
Language		slo
Abstract		Alcohol use can increase host susceptibility to infections caused by bacterial and viral pathogens. Impaired host defence after alcohol exposure appears is linked to a combination of decreased inflammatory response, mediated by macrophages. altered cytokine production, and abnormal reactive oxygen intermediate generation. Decreased antigen presenting cell function appears to be a key element in the ethanol-induced decrease in cell-mediated immunity. In addition, an induction of Th2 prevail over Thl. That causes increased levels of low efficient immunoglobulines, but as a whole the immune response in alcoholics become less efficient.
Descriptors		ALCOHOLISM IMMUNE SYSTEM INFLAMMATION CYTOKINES PHAGOCYTES LYMPHOCYTES ALCOHOL DRINKING